Metformin

Metformin is a widely prescribed diabetes medication that has garnered significant attention for its potential anti-cancer properties.
Epidemiological studies and laboratory research suggest it may reduce cancer risk, inhibit tumor growth, and enhance the effectiveness of standard cancer treatments.

Why Metformin Is Being Studied for Cancer

  • Activates AMPK pathway, which regulates cell growth and metabolism

  • May inhibit mTOR signaling involved in cancer cell proliferation

  • Shows potential to reduce insulin and IGF-1 levels linked to cancer growth

  • Demonstrates ability to target cancer stem cells

  • Extensive safety data from decades of diabetes use

Cancer Types Being Studied

  • Breast cancer

  • Colorectal cancer

  • Prostate cancer

  • Pancreatic cancer

  • Lung cancer

  • Ovarian cancer

  • Endometrial cancer

Related Topics in Our Archive

  • Metformin and chemotherapy

  • Metformin AMPK cancer

  • Metformin cancer prevention

  • Metformin dosage oncology

  • Metformin cancer stem cells

Common Research Questions

  • What dosages are used in cancer clinical trials?

  • Does metformin benefit non-diabetic cancer patients?

  • How does metformin interact with chemotherapy?

  • What are the side effects relevant to cancer patients?

What Researchers Are Studying

  • Mechanisms of action in cancer metabolism

  • Combination with immunotherapy and chemotherapy

  • Cancer prevention in high-risk populations

  • Optimal dosing for oncology applications

Browse Metformin Research

→ Search our archive for "metformin"

Disclaimer

This page is for informational purposes only. Always consult your oncologist before adding any supplement to your treatment plan.