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Methodology

Biomarkers & Diagnostics Research

Explore genetic markers, diagnostic tools, and testing methods for precision cancer care.

đŸ§Ŧ TP53

Tumor suppressor gene - most commonly mutated in human cancers

đŸ§Ŧ KRAS

Oncogene frequently mutated in pancreatic, colorectal, and lung cancers

đŸ§Ŧ EGFR

Receptor tyrosine kinase - target for lung cancer therapy

đŸ§Ŧ HER2

Growth factor receptor overexpressed in breast and gastric cancers

đŸ§Ŧ BRCA1

Hereditary breast and ovarian cancer gene

đŸ§Ŧ BRCA2

Hereditary breast and ovarian cancer gene

đŸ§Ŧ PD-L1

Immune checkpoint protein - predictor for immunotherapy response

đŸ§Ŧ ALK

Fusion gene target in non-small cell lung cancer

đŸ§Ŧ ROS1

Receptor tyrosine kinase fusion in lung cancer

đŸ§Ŧ BRAF

Oncogene mutated in melanoma and colorectal cancer

đŸ§Ŧ MSI-H

DNA mismatch repair deficiency - immunotherapy biomarker

đŸ§Ŧ PIK3CA

Oncogene frequently mutated in breast cancer

đŸ§Ŧ NTRK

Fusion gene target across multiple tumor types

đŸ§Ŧ MET

Receptor tyrosine kinase target in lung cancer

đŸ§Ŧ RET

Fusion gene target in thyroid and lung cancers

đŸ§Ŧ Liquid Biopsies

Blood-based cancer detection and monitoring methods

đŸ§Ŧ ctDNA Testing

Circulating tumor DNA analysis for cancer detection

đŸ§Ŧ Tumor Mutation Burden

Genomic biomarker predicting immunotherapy response

Methodology